Young Investigator’s Award Acceptance Remarks:
Regenerative Approaches to Wound Healing Using hADSC Sheets
京都大学大学院医学研究科形成外科学
趙 倩楠
My name is Qiannan Zhao, and I am affiliated with the Department of Plastic and Reconstructive Surgery, Graduate School of Medicine,Kyoto University. I am sincerely honored to receive the Young Investigator’s Award at the 55th Annual Meeting of the Japanese Society for Wound Healing.
My academic background is in plastic and reconstructive surgery, and my research interest lies in regenerative medicine and wound healing. Through both clinical and research experience, I have become increasingly aware of the difficulties involved in treating chronic and refractory wounds.Diabetic wounds remain a major clinical challenge because of persistent inflammation, impaired angiogenesis, and delayed tissue repair. These clinical needs have led me to focus on stem cell-based therapeutic strategies for improving the wound healing process.
The study for which I received this award examined the therapeutic potential of multilayer human adipose-derived stromal cell (hADSC) sheets in wound models. Compared with conventional cell suspension delivery, cell sheet technology may provide advantages such as preservation of extracellular matrix and improved local cell retention after transplantation. In our study, hADSC sheets showed favorable effects on tissue repair, including enhanced granulation tissue formation, angiogenesis, and accumulation of reparative macrophages. These findings suggest that cell sheet-based therapy may offer a promising approach for improving the wound healing environment.
I would like to express my sincere gratitude to my supervisors, collaborators, and the Society for their generous support and encouragement. I hope to continue contributing to the field of wound healing by bridging basic research and clinical application.